Serenity Forge, the company publishing the "newly updated version" of LISA: The Painful and LISA: The Joyful announced on their website, on behalf of itself and Dingaling Productions, that both games would receive changes due to some of the platforms it will be released in, stating:
We feel confident in the direction and purpose of LISA’s content, but we also know that certain platforms have regulations that we have to follow.
True to that, the Playstation version is unsurprisingly stated to have the most modifications, changing cigarettes to candies and alcohol to soda. They say
Basically, the changes are not a big deal. despite apparently being a big enough deal they needed to be done in the first place.
But censorship is also present in every other version. The Salvation Rangers and Junior's flashback sequence will receive unspecified alterations on all platforms including PC, where the original versions were released with no problems. Serenity Forge imply wanting to reach a larger audience, stating
ultimately it became an exciting prospect to alter some content in a small way in hopes that it welcomes and includes more players.